When you get CellCept from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. It can be prescribed after a heart, kidney, or liver transplant with other immunosuppressant drugs. Researchers wanted to see how effective each treatment was at preventing treatment failure. This helps ensure you have a consistent amount of the drug in your body. Possibly. Before you start CellCept, tell your doctor about any medications youre taking. See. However, this drug hasnt been studied in breastfeeding people. (See. This is especially true for birth control pills that contain the active drug levonorgestrel. They can recommend ways to treat this side effect. You may temporarily store the tablets at temperatures of 59F to 86F (15C to 30C), such as when traveling. If you would like to notify the FDA about a side effect youve had with CellCept, you can do so through MedWatch. Both drugs were given with corticosteroids and cyclosporine (Neoral). This card may help lower the cost of the drug for you. Some vaccines may not work as well during treatment with CellCept. Females who take Cellcept during pregnancy have a higher risk of miscarriage during the first 3 months (first trimester), and a higher risk that their baby will be born with birth defects. You may need to avoid crowds and wash your hands often. No, CellCept isnt a chemotherapy drug. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Weight gain is also a possible symptom of organ rejection. . If you have trouble swallowing the tablets or capsules, talk with your doctor. by visiting the Risk Evaluation and Mitigation Strategy (REMS) website at, unexplained fever, prolonged tiredness, weight loss or lymph node swelling, a brown or black skin lesion with uneven borders, or one part of the lesion does not look like the other, shingles, other herpes infections, and cytomegalovirus (CMV). Highly clinically significant. These infections may lead to serious outcomes, including the need to be hospitalized, and even death. Taking CellCept while you have this enzyme deficiency can cause increased levels of . This can make CellCept less effective. Studies in rats that were given CellCept showed the drug was present in milk. The purpose of this registry is to gather information about the health of you and your baby. Here are answers to some frequently asked questions about CellCept. In clinical studies: In these studies, it isnt known how many people may have died from a serious infection while using other treatments. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The IV infusion is given within 24 hours of a transplant. CellCept is used with other medicines containing cyclosporine and corticosteroids. CellCept is typically taken twice daily. Your doctor may want to monitor your treatment with CellCept more closely. (Having a stable transplant means you arent experiencing any symptoms of organ rejection. Do not crush, chew, or split the tablets. You and your doctor will decide if you will take CellCept or breastfeed. In some cases, your doctor may lower your CellCept dosage or have you stop treatment with the drug. The liquid should be stored at room temperature. Its FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. The link you have selected will take you away from this site to one that is not owned or controlled by Genentech, Inc. Genentech, Inc. makes no representation as to the accuracy of the information contained on sites we do not own or control. Prograf can be taken with or without food. If youre interested in finding an alternative to CellCept, talk with your doctor. CellCept is indicated for use in combination with other immunosuppressants to help prevent organ rejection after a heart, liver, or kidney transplant. Avoid raw sprouts, such as alfalfa sprouts. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. * This is a partial list of mild side effects from CellCept. CellCept isnt FDA-approved to treat lupus. View interaction reports for CellCept (mycophenolate mofetil) and the medicines listed below. The most common side effects of CellCept include: Side effects that can happen more often in children than in adults taking CellCept include: These are not all of the possible side effects of CellCept. However, data from pregnancy registries shows that 45% to 49% of people who took CellCept while pregnant had a pregnancy loss in the first 3 months of their pregnancy. Then take your next dose at its usual time. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites. However, clinical guidelines recommend using CellCept for this purpose in people who also have signs of kidney disease. Serious side effects from CellCept can occur. It can also cause swelling of the ankles. However, as soon as CellCept capsules, tablets, or liquid can be swallowed, discontinue the infusion form. Examples of birth control pills that contain levonorgestrel include Seasonique and Twirla. Before taking CellCept, talk with your doctor about your health history. They can discuss with you the risks and benefits of continuing your CellCept treatment. This means taking your dose either 1 hour before eating or 2 hours after eating. Don't open, cut, crush, or chew them. Tell them about all prescription, over-the-counter, and other drugs you take. According to the manufacturer, Novo Nordisk, people who are taking Ozempic and experience nausea should consider doing the following: Eat slowly. Moderately clinically significant. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. A boxed warning is the most serious warning from the FDA. CellCept is used to prevent organ rejection in patients who are at least three months of age who have received a liver transplant, a heart transplant, or a kidney transplant. Do not take any new medicine without talking with your doctor. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. In clinical studies of adults, CellCept was compared with azathioprine and a placebo (a treatment with no active drug). Your doctor will likely check your red blood cell count before you start using CellCept. (Azathioprine is an antirejection drug, like CellCept.) CellCept will stay in your system for about 1 week after your last dose. It is indicated for use in adults and children ages 3 months and older. Before you start using CellCept, be sure to tell your doctor if you take any PPIs. Its important to note that your results while using CellCept may vary from those seen in clinical studies. The results showed that: It isnt known how many people may have had a rash after using a placebo or after using CellCept for other types of transplants. Its also supported by additional data from use in children. A live vaccine contains a weakened form of the virus or bacteria that it helps prevent infection from. * Organ rejection occurs when the immune system attacks a transplanted organ. To learn about the cost of CellCept infusion, talk with your doctor. Brown rice. Warnings This drug has boxed warnings. Email this report to a friend, doctor, or patient. Do not take with food unless your doctor approves. CellCept has boxed warnings for these side effects. They may have a preference for one version or the other. These serious infections can include: Call your doctor right away if you have any of the following signs and symptoms of infection: SeeWhat are the possible side effects of CellCept?for information about other serious side effects. Weight gain wasnt a side effect reported in clinical studies of CellCept. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. To learn about using Prograf in children, talk with your childs doctor. To learn more, see the CellCept use with other drugs section. It works by preventing immune cells from multiplying. CellCept contains the active ingredient mycophenolate mofetil. French fries and potato chips are often very high in calories and . If you have questions about using CellCept with phosphate binders, talk with your doctor. As with all medications, the cost of CellCept can vary. If you miss a dose of CellCept, or you are not sure when you took your last dose, take your prescribed dose of CellCept as soon as you remember. You dont have to avoid eating any specific type of food during your CellCept treatment. The following lists contain some of the key side effects that may occur while taking CellCept. Call your healthcare provider right away. CellCept alcohol/food interactions There is 1 alcohol/food interaction with CellCept (mycophenolate mofetil). If you have questions about whether CellCept is right for your child, talk with their doctor. These lists dont include all possible side effects that may occur with each drug. Signs of skin cancer include moles or skin spots that are new, have grown, or have changed color. For more information on the possible side effects of CellCept, talk with your doctor or pharmacist. Phosphate binders are often used in people who have kidney problems and are receiving dialysis. Your . Cellcept can cause serious side effects, including: Increased risk of loss of a pregnancy (miscarriage) and higher risk of birth defects. This happens because the immune system doesnt recognize the new organ as part of your body. CellCept is an immunosuppressant (a drug that weakens your immune system). Stem cell therapy may help reduce inflammation and build up healthy cells in the body. If youre taking a form of CellCept thats swallowed, in most cases you should take it on an empty stomach. Hair loss isnt a side effect of CellCept thats been reported in clinical studies. Also tell them about any vitamins, herbs, and supplements you use. The insurance company will review the prior authorization request and decide if the drug will be covered. (Scleroderma is a condition that affects the bodys skin and tissues.) Other interactions can increase side effects or make them more severe. The expiration date helps guarantee that the medication is effective during this time. Below are examples of off-label uses for CellCept. These lists contain examples of serious side effects that can occur with CellCept, with Myfortic, or with both drugs (when taken individually). The risk of pregnancy loss is highest during the first 3 months of pregnancy. Possibly. However, chemotherapy drugs cant tell the difference between healthy cells and cancer cells. stop taking CellCept. Many of these side effects may go away within a few days or a couple of weeks. Capsules should be stored at room temperature. Tell your doctor right away if you become pregnant while using CellCept. If youre concerned about hair loss while using CellCept, talk with your doctor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In addition to the use listed above, CellCept is also used off-label for other purposes at times. Hepatitis viruses can affect how your liver works. This may occur if you develop an infection or have an existing infection that worsens. There are 308 drugs known to interact with prednisone, triamcinolone, prednisolone, tacrolimus, azathioprine, cyclosporine, mycophenolate mofetil, cyclophosphamide, cortisone, Imuran. Genentech, the manufacturer of CellCept, offers the CellCept Co-pay Card. The generic is considered to be as safe and effective as the original drug. Its approved for use in adults and children ages 3 months and older. In most cases, you should take CellCept on an empty stomach (1 hour before eating or 2 hours after eating). The use of CellCept and Myfortic in preventing organ rejection after kidney transplant has been directly compared in a clinical study. Therefore, this information was not gathered in a clinical study overseen by researchers. CellCept is an antirejection drug that works by preventing immune cells from multiplying. Swallow the capsules and tablets whole. To learn more, call 800-617-8191, visit the registry website, or talk with your doctor. (Skin spots may be discolored, scaly, or crusty.). To give an example, for a child whose body surface area is 1.25 m2, the typical dose is 750 mg taken twice per day. How and where you store CellCept is slightly different for each form of the drug: If you no longer need to take CellCept capsules, tablets, or liquid and have leftover medication, its important to dispose of it safely. They can discuss ways to lower your risk. Take mycophenolate (CellCept) every 12 hours on an empty stomach, unless your healthcare provider has told you to take it with food. CellCept works by preventing immune cells from multiplying. To help make sure you dont miss a dose, try using a medication reminder. They can help determine if these medications will affect the breakdown of CellCept in your body. In addition, the percentage of people who may have had depression while using CellCept for other types of transplants isnt known. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using CellCept. CellCept and Prograf are prescribed for similar uses. To help prevent organ rejection, dont stop taking CellCept without first discussing the risks with your doctor. Choose high-fiber whole grains like: Whole wheat bread or grains made with whole wheat flour. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Myfortic (when taken individually). In rare cases, taking CellCept can lead to serious infections that cause sepsis (a life threatening response to an infection) or death. Your doctor may prescribe a different treatment for your condition. Administration with food decreases the concentration of mycophenolic acid by 40%. Females using CellCept should use effective birth control while taking the drug and for at least 6 weeks after their last dose. CellCept and Myfortic have some similar side effects and others that vary. birth control pills (oral contraceptives). Before starting treatment, talk with your doctor about your risk for cancer while using CellCept. If you have questions about using CellCept with other medications, talk with your doctor. However, you may store the liquid at temperatures of 59F to 86F (15C to 30C) for up to 60 days. Eat smaller meals. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. . Avoid soft mold-ripened and blue-veined cheeses such as Brie, Camembert, Roquefort, Stilton, Gorgonzola and Bleu or other soft, unpasteurized cheeses. Bactrim (sulfamethoxazole / trimethoprim), Email this report to a friend, doctor, or patient. Steer clear of inflammatory foods such as grains and legumes, nightshades, gluten, and dairy. 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